10th International Symposium On Targeted Alpha Therapy Session IV: Nanocarriers

Kanazawa, Japan (UroToday.com) There is a substantial problem with binding the radioisotope to a molecular structure. Isotopes like Ra223 and Ac225 have decay chains that emit a total of four alphas. When the first decay occurs, the recoil of the daughter nucleus is sometimes sufficient to break the molecular bond holding the radioisotope. For the isotopes above, one of the daughter nuclei has a long enough half-life to travel through the body. This is doubly bad since not only is the alpha lost to the tumor site but the free isotope may damage healthy organs, especially the liver and kidneys.

The solution to these problems is to capture the radioisotope within a mechanical structure of a size (10’s of nanometers) and composition that alpha particles can escape but the daughter is retained. Either a coating or the composition of the nanocarrier is such that it can still be attached to antibody that targets the tumor. Read more.

How chemical 'clues' in diet can help identify human remains—and climate changes

SFU archaeology professor Mike Richards is studying how the chemical signatures from food and water consumed by humans and animals can provide clues to identifying human remains—and can also shed light on changes in climate.

The newly-named Canada Research Chair holder in Archaeological Science has established a lab at SFU to analyze isotopes, which are forms of chemical elements, that have been digested and incorporated into body tissues. “These chemical signatures record the diet, as well as the geographical location and climate when that tissue was formed for humans and animals,” explains Richards. Read more.

Piling on Pressure Solves Enduring Mystery About Metal’s Makeup

Scientists have solved a decade-long puzzle about lithium, an essential metal in cellphone and computer batteries. Using extreme pressure experiments and powerful supercomputing, the international team has unraveled the mystery of a fundamental property of lithium. Its atoms are arranged in a simple structure, and may be the first direct evidence of a quantum solid behavior in a metal. Read more.

Dune ecosystem modelling

Acacia longifolia, which is native to Australia, is a species which was cultivated in Portugal primarily to stabilize dunes and as an ornamental plant; now it has spread out uncontrollably in Portugal and into many ecosystems around the world. Using the acacia as an example, researchers show that the location has an effect on interaction with other species. Read more.